CELLEX

BioAxFlow

 > Patent N° WO2024/189527A1

Our bioreactor BioAxFlow is a device where, with the help of an external peristaltic pump and tubes, cell culture medium is continuously pumped into a vessel from the bottom, lifting the cells up, accessing the vessel and, eventually, allowing cell seeding on the scaffold.

BioAxFlow’s user-friendly modular system consists of 4 main components:

The base that allows both medium entry and exit thus, generates fluid dynamics suitable for efficient cell culture within the bioreactor chamber;

The scaffold stand designed to accommodate constructs/scaffolds of different geometries and sizes, customisable by the client;

The cap is equipped with sampling ports for cell sampling and threaded supports for vent plugs.

The glass cylinder, allowing for constant visual inspection of the content;

A complete “plug and play” solution for tissue engineering, combining innovation, versatility, and ease of use.

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Our solution presents seven main innovative characteristics:

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It can hold construct(s)/scaffold(s) of different geometries and dimensions. We design and produce customisable supports to hold constructs of different geometries.

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It allows automated cell seeding via the utilization of simple control valves.

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It achieves a homogeneous cell distribution.

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Our solution, thanks to the generation of its sophisticated fluid dynamics, allows cells to be distributed homogeneously upon the scaffold.

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Modular bioreactor system. Our system is modular and can incorporate more than a single fully integrated bioreactor, to perform multiple experiments in parallel.

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Fully transparent vessel for optical investigations.

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Suitable for suspension and anchorage-dependent cell culture.

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